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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1550709
Species: Mus musculus
RGD Object: Gene
Symbol: Cxcl10
Name: C-X-C motif chemokine ligand 10
Acc ID: CHEBI:22689
Term: bafilomycin A1
Definition: The most used of the bafilomycins, a family of toxic macrolide antibiotics derived from Streptomyces griseus.
Chemical ID: MESH:C040929
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cxcl10multiple interactionsISOCXCL10 (Homo sapiens)6480464CTDbafilomycin A1 inhibits the reaction [CpG ODN 2216 results in increased expression of CXCL10 protein]; bafilomycin A1 inhibits the reaction [gardiquimod results in increased expression of CXCL10 protein]; bafilomycin A1 inhibits the reaction [Poly I-C results in increased expression of CXCL10 protein]PMID:26682054
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