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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1550578
Species: Mus musculus
RGD Object: Gene
Symbol: St3gal4
Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 4
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
St3gal4decreases expressionEXP 6480464CTDBenzo(a)pyrene results in decreased expression of ST3GAL4 mRNAPMID:19770486
St3gal4affects methylationISOST3GAL4 (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of ST3GAL4 5' UTR; Benzo(a)pyrene affects the methylation of ST3GAL4 intron; Benzo(a)pyrene affects the methylation of ST3GAL4 promoterPMID:27901495 PMID:30157460
St3gal4increases methylationISOST3GAL4 (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased methylation of ST3GAL4 exonPMID:27901495
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