GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ace2 | increases response to substance | EXP | | 6480464 | CTD | ACE2 gene mutant form results in increased susceptibility to Thioacetamide | PMID:28845018 | Ace2 | multiple interactions | EXP | | 6480464 | CTD | ACE2 gene mutant form promotes the reaction [Thioacetamide results in increased activity of MMP9 protein]; ACE2 gene mutant form promotes the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]; ACE2 gene mutant form promotes the reaction [Thioacetamide results in increased expression of IL6 mRNA]; ACE2 gene mutant form promotes the reaction [Thioacetamide results in increased expression of MMP9 mRNA]; ACE2 gene mutant form promotes the reaction [Thioacetamide results in increased expression of TIMP1 mRNA]; ACE2 gene mutant form promotes the reaction [Thioacetamide results in increased expression of TNF mRNA] | PMID:28845018 | | ||||||||||||||||||||||
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