Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - TERM ANNOTATION REPORT

RGD ID: 1550238
Species: Mus musculus
RGD Object: Gene
Symbol: Fbxl12
Name: F-box and leucine-rich repeat protein 12
Acc ID: GO:0031146
Term: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Definition: The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.
Definition Source(s): PMID:15380083
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fbxl12involved_inIBAPANTHER:PTN001923412 or MGI:1354702 or UniProtKB:Q9UKT7 or TAIR:locus:2061136 or UniProtKB:Q9UF562290270GO_Central GO_REF:0000033
Go Back to source page   Continue to Ontology report