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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1550230
Species: Mus musculus
RGD Object: Gene
Symbol: Tnfrsf12a
Name: tumor necrosis factor receptor superfamily, member 12a
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfrsf12aincreases expressionEXP 6480464CTDDiethylnitrosamine results in increased expression of TNFRSF12A mRNAPMID:24535843
Tnfrsf12aincreases expressionISOTNFRSF12A (Homo sapiens)6480464CTDDiethylnitrosamine results in increased expression of TNFRSF12A mRNAPMID:21527772
Tnfrsf12aincreases expressionISOTnfrsf12a (Rattus norvegicus)6480464CTDDiethylnitrosamine results in increased expression of TNFRSF12A mRNAPMID:19638242
Tnfrsf12amultiple interactionsISOTnfrsf12a (Rattus norvegicus)6480464CTD[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNFRSF12A mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of TNFRSF12A mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of TNFRSF12A mRNAPMID:18164116 PMID:22129741 PMID:28943392
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