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GENE - TERM ANNOTATION REPORT

RGD ID: 14242097
Species: Sus scrofa
RGD Object: Gene
Symbol: MAP2K4
Name: mitogen-activated protein kinase kinase 4
Acc ID: DOID:0050933
Term: ovarian serous carcinoma
Definition: An ovarian carcinoma that has_material_basis_in the lining of the ovary and produces a serum-like fluid. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Serous_carcinoma "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MAP2K4 ISOMAP2K4 (Homo sapiens)9068941RGDovarian serous carcinoma; DNA:loss of heterozygosity:tumor:24/28 (86%) of high-grade tumors, also decreased expression in 96/128 (75%) of tumorsPMID:16627982 REF_RGD_ID:2293332
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