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GENE - TERM ANNOTATION REPORT

RGD ID: 14241291
Species: Sus scrofa
RGD Object: Gene
Symbol: FASLG
Name: Fas ligand
Acc ID: GO:0008625
Term: extrinsic apoptotic signaling pathway via death domain receptors
Definition: The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with a ligand binding to a death domain receptor on the cell surface, and ends when the execution phase of apoptosis is triggered.
Definition Source(s): GOC:mah, GOC:mtg_apoptosis
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
FASLG ISOFaslg (Rattus norvegicus)9068941RGD PMID:16689665 REF_RGD_ID:1582444
FASLGinvolved_inIEAUniProtKB:P41047 or UniProtKB:P48023 or ensembl:ENSMUSP00000000834 or ensembl:ENSP00000356694150520179Ensembl GO_REF:0000107
FASLGinvolved_inIBAMGI:99255 or PANTHER:PTN002607446 or Faslg (Rattus norvegicus) or UniProtKB:P48023150520179GO_Central GO_REF:0000033
FASLGacts_upstream_of_or_withinISOFasl (Mus musculus)9068941MGI PMID:10588860 PMID:15039234

PMID:10588860 PMID:15039234
FASLGacts_upstream_of_or_withinISOFASLG (Homo sapiens)9068941MGI PMID:26582200

PMID:26582200
FASLGinvolved_inIEAPANTHER:PTHR11471:SF33150520179TreeGrafter GO_REF:0000118
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