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GENE - TERM ANNOTATION REPORT

RGD ID: 14237345
Species: Sus scrofa
RGD Object: Gene
Symbol: FBXW7
Name: F-box and WD repeat domain containing 7
Acc ID: GO:0031146
Term: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Definition: The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.
Definition Source(s): PMID:15380083
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
FBXW7involved_inIEAUniProtKB:Q8VBV4 or UniProtKB:Q969H0 or ensembl:ENSMUSP00000103306 or ensembl:ENSP00000281708150520179Ensembl GO_REF:0000107
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