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RGD ID: 14187349
Species: Sus scrofa
RGD Object: Gene
Symbol: CASP8
Name: caspase 8
Acc ID: GO:0006919
Term: activation of cysteine-type endopeptidase activity involved in apoptotic process
Definition: Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process.
Definition Source(s): GOC:al, GOC:dph, GOC:jl, GOC:mtg_apoptosis, GOC:tb, PMID:14744432, PMID:18328827, Wikipedia:Caspase
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CASP8 IBAFB:FBgn0020381, MGI:MGI:1261423, MGI:MGI:1277950, PANTHER:PTN00004794814298760GO_Central (PMID:21873635)

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.