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GENE - TERM ANNOTATION REPORT

RGD ID: 14177270
Species: Sus scrofa
RGD Object: Gene
Symbol: PLAU
Name: plasminogen activator, urokinase
Acc ID: DOID:5844
Term: myocardial infarction
Definition: A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia. (DO)
Definition Source(s): https://en.wikipedia.org/wiki/Myocardial_infarction "DO" "DO", https://www.ncbi.nlm.nih.gov/pubmed/17951287 "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PLAU ISOPlau (Rattus norvegicus)9068941RGDmRNA, protein:increased expression:myocardiumPMID:20952728 REF_RGD_ID:6484133
PLAU ISOPLAU (Homo sapiens)9068941RGD PMID:17653104 REF_RGD_ID:6484145
PLAU ISOPLAU (Homo sapiens)9068941RGDDNA:SNP:3' utr:c.*141C>T (rs4065) (human)PMID:20518747 REF_RGD_ID:6484126
PLAU ISOPLAU (Homo sapiens)9068941CTDCTD Direct Evidence: marker/mechanism|therapeuticPMID:1908371 PMID:2174952 PMID:2382605 PMID:3068399 PMID:3984876 PMID:8416330
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