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GENE - TERM ANNOTATION REPORT

RGD ID: 14173345
Species: Sus scrofa
RGD Object: Gene
Symbol: STAT1
Name: signal transducer and activator of transcription 1
Acc ID: DOID:9004484
Term: Sepsis
Definition: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
Definition Source(s): MESH:D018805
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
STAT1 ISOStat1 (Rattus norvegicus)9068941RGDprotein:increased activity:liver, lung, small intestinePMID:17067487 REF_RGD_ID:2291905
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