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RGD ID: 14159956
Species: Sus scrofa
RGD Object: Gene
Symbol: ADD3
Name: adducin 3
Acc ID: GO:0005856
Term: cytoskeleton
Definition: Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
Definition Source(s): GOC:mah, ISBN:0198547684, PMID:16959967
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ADD3 IEAUniProtKB:Q9QYB5, ensembl:ENSMUSP0000002599914298760Ensembl GO_REF:0000107
ADD3 IBAMGI:MGI:1351615, MGI:MGI:87918, PANTHER:PTN000072560, RGD:204314298760GO_Central (PMID:21873635)

ADD3 IEAInterPro:IPR02777214298760InterPro GO_REF:0000002
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.