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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 14134172
Species: Sus scrofa
RGD Object: Gene
Symbol: CASP3
Name: caspase 3
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CASP3increases expressionEXP 6480464CTDLipopolysaccharides results in increased expression of CASP3 proteinPMID:31669396 PMID:32877744
CASP3multiple interactionsEXP 6480464CTD3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CASP3 protein]; [deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CASP3 protein; Flavones inhibits the reaction [Lipopolysaccharides results in increased expression of CASP3 protein]; MAP1LC3B protein affects the reaction [[deoxynivalenol co-treated with Lipopolysaccharides] results in increased expression of CASP3 protein]PMID:31669396 PMID:32877744
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