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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 14134172
Species: Sus scrofa
RGD Object: Gene
Symbol: CASP3
Name: caspase 3
Acc ID: CHEBI:15553
Term: prostaglandin F2alpha
Definition: A prostaglandins Falpha that is prosta-5,13-dien-1-oic acid substituted by hydroxy groups at positions 9, 11 and 15. It is a naturally occurring prostaglandin used to induce labor.
Chemical ID: MESH:D015237
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CASP3increases activityEXP 6480464CTDDinoprost results in increased activity of CASP3 proteinPMID:20739670
CASP3increases expressionEXP 6480464CTDDinoprost results in increased expression of CASP3 mRNAPMID:20739670
CASP3multiple interactionsEXP 6480464CTD[epostane co-treated with Dinoprost] results in increased activity of CASP3 protein; Dinoprost promotes the reaction [epostane results in increased expression of CASP3 mRNA]; epostane promotes the reaction [Dinoprost results in increased expression of CASP3 mRNA]PMID:20739670
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