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GENE - TERM ANNOTATION REPORT

RGD ID: 14121243
Species: Sus scrofa
RGD Object: Gene
Symbol: TGFB1
Name: transforming growth factor beta 1
Acc ID: DOID:9001573
Term: Experimental Liver Cirrhosis
Definition: Experimentally induced chronic injuries to the parenchymal cells in the liver to achieve a model for LIVER CIRRHOSIS.
Definition Source(s): MESH:D008106
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TGFB1 ISOTgfb1 (Rattus norvegicus)9068941RGDprotein:increased expression:liverPMID:16009107 REF_RGD_ID:1601595
TGFB1 ISOTgfb1 (Mus musculus)9068941RGDmRNA:increased expression:liver (mouse)PMID:28465467 REF_RGD_ID:39939037
TGFB1onsetISOTgfb1 (Rattus norvegicus)9068941RGDassociated with extrahepatic cholestasisPMID:30243650 REF_RGD_ID:14985234
TGFB1treatmentISOTgfb1 (Rattus norvegicus)9068941RGD PMID:30092114 REF_RGD_ID:14985231
TGFB1treatmentISOTgfb1 (Mus musculus)9068941RGD PMID:27528511 REF_RGD_ID:14995475
TGFB1treatmentISOTgfb1 (Mus musculus)9068941RGDassociated with Chemical and Drug Induced Liver InjuryPMID:28390311 REF_RGD_ID:14985232
TGFB1 ISOTGFB1 (Homo sapiens)9068941CTDCTD Direct Evidence: marker/mechanism|therapeuticPMID:12586293 PMID:15772939 PMID:16579972 PMID:26806094 PMID:27605418
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