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GENE - TERM ANNOTATION REPORT

RGD ID: 14103484
Species: Sus scrofa
RGD Object: Gene
Symbol: CAT
Name: catalase
Acc ID: DOID:1824
Term: status epilepticus
Definition: A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30)
Definition Source(s): MESH:D013226
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CAT ISOCAT (Homo sapiens)9068941CTDCTD Direct Evidence: marker/mechanism|therapeuticPMID:15245787 PMID:15752349 PMID:17383094 PMID:18096215
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