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GENE - TERM ANNOTATION REPORT

RGD ID: 14070176
Species: Sus scrofa
RGD Object: Gene
Symbol: DPYD
Name: dihydropyrimidine dehydrogenase
Acc ID: DOID:9008443
Term: Colorectal Neoplasms
Definition: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
Definition Source(s): MESH:D015179
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
DPYD ISODPYD (Homo sapiens)9068941CTDCTD Direct Evidence: marker/mechanismPMID:15222106 PMID:15814641 PMID:17047489 PMID:17611699 PMID:19020767
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