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GENE - TERM ANNOTATION REPORT

RGD ID: 14056892
Species: Sus scrofa
RGD Object: Gene
Symbol: CCL2
Name: chemokine (C-C motif) ligand 2
Acc ID: DOID:9002311
Term: Experimental Autoimmune Myocarditis
Definition: Experimental autoimmune myocarditis is a model of inflammatory heart disease and subsequent dilated cardiomyopathy (DCM). Inoculation with purified cardiac myosin combined with FREUND'S ADJUVANT triggers the disease in rats and mice.
Definition Source(s): PMID:11274001, PMID:15546794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CCL2disease_progressionISOCcl2 (Rattus norvegicus)9068941RGDmRNA, protein:increased expression:heart, serum (rat)PMID:11472393 REF_RGD_ID:8549580
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