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GENE - TERM ANNOTATION REPORT

RGD ID: 14056892
Species: Sus scrofa
RGD Object: Gene
Symbol: CCL2
Name: chemokine (C-C motif) ligand 2
Acc ID: DOID:1936
Term: atherosclerosis
Definition: A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA. (DO)
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CCL2severityISOCcl2 (Mus musculus)9068941RGDmRNA:increased expression:aorta (mouse)PMID:15823270 REF_RGD_ID:7401235
CCL2treatmentISOCcl2 (Mus musculus)9068941RGD PMID:11486244 PMID:23650230 REF_RGD_ID:401842363 REF_RGD_ID:8548896
CCL2 ISOCCL2 (Homo sapiens)9068941CTDCTD Direct Evidence: marker/mechanismPMID:12677255 PMID:12928151 PMID:20720404
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