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GENE - TERM ANNOTATION REPORT

RGD ID: 14045563
Species: Sus scrofa
RGD Object: Gene
Symbol: SOD1
Name: superoxide dismutase 1
Acc ID: DOID:0060224
Term: atrial fibrillation
Definition: A heart conduction disease that is characterized by uncoordinated electrical activity in the heart's upper chambers (the atria), which causes the heartbeat to become fast and irregular and has symptoms palpitations, weakness, fatigue, lightheadedness, dizziness, confusion, shortness of breath and chest pain. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Atrial_fibrillation "DO" "DO", http://www.mayoclinic.org/diseases-conditions/atrial-fibrillation/basics/definition/con-20027014 "DO" "DO", http://www.nhlbi.nih.gov/health/health-topics/topics/af "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SOD1 ISOSOD1 (Homo sapiens)9068941RGDassociated with Mitral Valve Insufficiency;mRNA, protein:increased expression:posterior wall of left atrium (human)PMID:21954878 REF_RGD_ID:8655869
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