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GENE - TERM ANNOTATION REPORT

RGD ID: 14041463
Species: Sus scrofa
RGD Object: Gene
Symbol: IDH2
Name: isocitrate dehydrogenase (NADP(+)) 2
Acc ID: DOID:9007502
Term: Brain Neoplasms
Definition: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
Definition Source(s): MESH:D001932
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IDH2 ISOIDH2 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Brain NeoplasmsPMID:20946881 PMID:21250968 PMID:21596855 PMID:21997850 PMID:22160010 PMID:22397365 PMID:22417203 PMID:22616558 PMID:22898539 PMID:23949315 PMID:24606448 PMID:25157968 PMID:26619011
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