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GENE - TERM ANNOTATION REPORT

RGD ID: 14001478
Species: Sus scrofa
RGD Object: Gene
Symbol: MRE11
Name: MRE11 homolog, double strand break repair nuclease
Acc ID: GO:0031573
Term: mitotic intra-S DNA damage checkpoint signaling
Definition: A mitotic cell cycle checkpoint that slows DNA synthesis in response to DNA damage by the prevention of new origin firing and the stabilization of slow replication fork progression.
Definition Source(s): GOC:vw
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MRE11involved_inIEAUniProtKB:Q61216 or ensembl:ENSMUSP00000034405150520179Ensembl GO_REF:0000107
MRE11involved_inIBAMGI:1100512 or PANTHER:PTN000015646 or PomBase:SPAC13C5.07150520179GO_Central GO_REF:0000033
MRE11acts_upstream_of_or_withinISOMGI:30270369068941MGI PMID:14690604 PMID:18614044

PMID:14690604 PMID:18614044
MRE11involved_inIEAPANTHER:PTHR10139:SF1150520179TreeGrafter GO_REF:0000118
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