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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 14000791
Species: Sus scrofa
RGD Object: Gene
Symbol: RYR1
Name: ryanodine receptor 1
Acc ID: CHEBI:33324
Term: strontium atom
Definition: An alkaline earth metal atom that has formula Sr.
Chemical ID: MESH:D013324
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
RYR1increases activityEXP 6480464CTDStrontium results in increased activity of RYR1 proteinPMID:11278295
RYR1multiple interactionsEXP 6480464CTDDantrolene inhibits the reaction [Strontium promotes the reaction [Ryanodine binds to RYR1 protein]]; Strontium promotes the reaction [Ryanodine binds to RYR1 protein mutant form]; Strontium promotes the reaction [Ryanodine binds to RYR1 protein]PMID:11278295
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