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GENE - TERM ANNOTATION REPORT

RGD ID: 13994648
Species: Sus scrofa
RGD Object: Gene
Symbol: CTNNB1
Name: catenin beta 1
Acc ID: DOID:1911
Term: endodermal sinus tumor
Definition: A germ cell cancer that has_material_basis_in cells that line the yolk sac of the embryo. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Endodermal_sinus_tumor "DO" "DO", http://en.wikipedia.org/wiki/Germ_cell_tumor "DO" "DO", http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=GB&Expert=876 "DO" "DO", https://www.cincinnatichildrens.org/health/y/yolk-sac/ "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CTNNB1 ISOCTNNB1 (Homo sapiens)9068941RGDmRNA, protein:increased expression, increased activity:tumor:high expression in 100%, increased nuclear accumulation in 50-70% of tumorsPMID:16822086 REF_RGD_ID:2298800
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