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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 13948182
Species: Sus scrofa
RGD Object: Gene
Symbol: CLDN1
Name: claudin 1
Acc ID: CHEBI:90705
Term: SB 203580
Definition: A member of the class of imidazoles carrying 4-methylsulfinylphenyl, 4-pyridyl and 4-fluorophenyl substituents at positions 2, 4 and 5 respectively. An inhibitor of mitogen-activated protein kinase.
Chemical ID: MESH:C093642
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CLDN1multiple interactionsEXP 6480464CTD[SB 203580 co-treated with theanine] inhibits the reaction [Lipopolysaccharides results in decreased expression of CLDN1 mRNA]; SB 203580 inhibits the reaction [Hydrogen Peroxide results in decreased expression of CLDN1 mRNA]; SB 203580 inhibits the reaction [Hydrogen Peroxide results in decreased expression of CLDN1 protein]; SB 203580 inhibits the reaction [Lipopolysaccharides results in decreased expression of CLDN1 mRNA]PMID:37271275 PMID:38438008
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