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GENE - TERM ANNOTATION REPORT

RGD ID: 13939093
Species: Sus scrofa
RGD Object: Gene
Symbol: RB1CC1
Name: RB1 inducible coiled-coil 1
Acc ID: GO:1990316
Term: Atg1/ULK1 kinase complex
Definition: A protein complex consisting of Atg1 (or Atg1 homologs e.g. ULK1, ULK2 in mammals) and Atg13 along with other proteins that regulate its function (e.g. Atg17 in yeast or RB1CC1(FIP200) in mammals). This complex has serine/threonine protein kinase activity and is involved in autophagosome formation.
Definition Source(s): GOC:bhm, GOC:DOS, GOC:rb, PMID:15743910, PMID:19211835, PMID:19258318, PMID:19597335, PMID:22885598
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
RB1CC1located_inISORB1CC1 (Homo sapiens)9068941ComplexPortal PMID:19597335

PMID:19597335
RB1CC1part_ofIEAUniProtKB:Q8TDY2 or UniProtKB:Q9ESK9 or ensembl:ENSMUSP00000027040 or ensembl:ENSP00000025008150520179Ensembl GO_REF:0000107
RB1CC1part_ofIBAFB:FBgn0037363 or MGI:1341850 or PANTHER:PTN000996416 or PomBase:SPAC7D4.04 or UniProtKB:Q8TDY2150520179GO_Central GO_REF:0000033
RB1CC1part_ofIEAPANTHER:PTHR13222:SF1150520179TreeGrafter GO_REF:0000118
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