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GENE - TERM ANNOTATION REPORT

RGD ID: 13920827
Species: Sus scrofa
RGD Object: Gene
Symbol: DRD2
Name: dopamine receptor D2
Acc ID: DOID:14330
Term: Parkinson's disease
Definition: A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Parkinson%27s_disease "DO" "DO", https://pubmed.ncbi.nlm.nih.gov/26474316/ "DO" "DO", https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877503/ "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
DRD2 ISODrd2 (Rattus norvegicus)9068941RGDprotein:increased expression:striatum (rat)PMID:18289173 REF_RGD_ID:2311585
DRD2 ISODRD2 (Homo sapiens)9068941CTDCTD Direct Evidence: therapeuticPMID:8558425
DRD2 ISODrd2 (Mus musculus)9068941MouseDOOMIM:168600 | OMIM:300557 | OMIM:556500 | OMIM:602404 | OMIM:606852 | OMIM:607688 | OMIM:610297 | OMIM:613164 | OMIM:613643 | OMIM:614251 
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