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GENE - TERM ANNOTATION REPORT

RGD ID: 13915338
Species: Sus scrofa
RGD Object: Gene
Symbol: EDN1
Name: endothelin 1
Acc ID: DOID:8252
Term: chronic rhinitis
Definition: A rhinitis which is persistent and long-lasting. It may occur with diseases such as syphilis, tuberculosis, rhinoscleroma, rhinosporidiosis, leishmaniasis, blastomycosis, histoplasmosis, and leprosy, all of which are characterized by the formation of inflamed lesions (granulomas) and the destruction of soft tissue, cartilage, and bone. Chronic rhinitis causes nasal obstruction, pus-filled discharge from the nose, and frequent bleeding. (DO)
Definition Source(s): http://www.merck.com/mmhe/sec19/ch221/ch221g.html?qt=chronic%20rhinitis&alt=sh "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
EDN1 ISOEDN1 (Homo sapiens)9068941RGDprotein:increased expression:inferior turbinate, nasal gland, inflammatory cell (human)PMID:8845175 REF_RGD_ID:8661738
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