Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - TERM ANNOTATION REPORT

RGD ID: 13888629
Species: Sus scrofa
RGD Object: Gene
Symbol: THOP1
Name: thimet oligopeptidase 1
Acc ID: GO:0004222
Term: metalloendopeptidase activity
Definition: Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
Definition Source(s): GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE, http://merops.sanger.ac.uk/about/glossary.htm#ENDOPEPTIDASE
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
THOP1 IBAMGI:MGI:1354165, PANTHER:PTN000211184, RGD:621518, SGD:S000000562, SGD:S00000161714298760GO_Central (PMID:21873635)

PMID:21873635
THOP1 IEAInterPro:IPR00156714298760InterPro GO_REF:0000002
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.