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RGD ID: 13888629
Species: Sus scrofa
RGD Object: Gene
Symbol: THOP1
Name: thimet oligopeptidase 1
Acc ID: GO:0004222
Term: metalloendopeptidase activity
Definition: Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
Definition Source(s): GOC:mah,,
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
THOP1 IBAMGI:MGI:1354165, PANTHER:PTN000211184, RGD:621518, SGD:S000000562, SGD:S00000161714298760GO_Central (PMID:21873635)

THOP1 IEAInterPro:IPR00156714298760InterPro GO_REF:0000002
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.