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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1359664
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Krt1
Name: keratin 1
Acc ID: CHEBI:47217
Term: arsane
Definition: An arsine that has formula 77.94542.
Chemical ID: MESH:D001151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Krt1decreases expressionEXP 6480464CTDArsenic results in decreased expression of KRT1 proteinPMID:34352348
Krt1affects methylationISOKRT1 (Homo sapiens)6480464CTDArsenic affects the methylation of KRT1 genePMID:25304211
Krt1increases expressionISOKRT1 (Homo sapiens)6480464CTDArsenic results in increased expression of KRT1 mRNA; Arsenic results in increased expression of KRT1 proteinPMID:11134558 PMID:19818359 PMID:35363433
Krt1multiple interactionsISOKRT1 (Homo sapiens)6480464CTD[sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of KRT1 mRNAPMID:32525701
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