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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1359623
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tuba4a
Name: tubulin, alpha 4A
Acc ID: CHEBI:27585
Term: selenomethionine
Definition: A selenoamino acid that is the selenium analogue of methionine.
Chemical ID: MESH:D012645
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tuba4aincreases glutathionylationISOTUBA4A (Homo sapiens)6480464CTDSelenomethionine results in increased glutathionylation of TUBA4A proteinPMID:31585128
Tuba4amultiple interactionsISOTUBA4A (Homo sapiens)6480464CTDSelenomethionine promotes the reaction [TUBA4A protein binds to FUS protein]; Selenomethionine promotes the reaction [TUBA4A protein binds to TIA1 protein]; TUBA4A mutant form results in increased abundance of [Selenomethionine binds to Selenium]PMID:28478440 PMID:31585128
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