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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1359615
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Dlst
Name: dihydrolipoamide S-succinyltransferase
Acc ID: CHEBI:35549
Term: perfluorooctanoic acid
Definition: A fluoroalkanoic acid that is perfluorinated octanoic acid.
Chemical ID: MESH:C023036
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dlstincreases expressionISODLST (Homo sapiens)6480464CTDperfluorooctanoic acid results in increased expression of DLST proteinPMID:26879310
Dlstmultiple interactionsISODlst (Mus musculus)6480464CTDDietary Fats, Unsaturated inhibits the reaction [perfluorooctanoic acid results in increased expression of DLST mRNA]PMID:23626681
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