Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   


RGD ID: 1359489
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nub1
Name: negative regulator of ubiquitin-like proteins 1
Acc ID: DOID:2843
Term: long QT syndrome
Definition: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.
Definition Source(s): MESH:D008133,
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 ISORGD:16021128554872ClinVarClinVar Annotator: match by term: Long QT syndrome

PMID:16470702, PMID:18348270, PMID:19443486, PMID:25606385, PMID:28492532
Go Back to source page   Continue to Ontology report


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.