GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1359360
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mef2a
Name: myocyte enhancer factor 2a
Acc ID: CHEBI:4317
Term: dantrolene
Definition: The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin.
Chemical ID: MESH:D003620
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTDDantrolene inhibits the reaction [Caffeine results in increased expression of MEF2A mRNA]

Dantrolene inhibits the reaction [Caffeine results in increased expression of MEF2A protein]

PMID:25093688
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.