GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1359360
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mef2a
Name: myocyte enhancer factor 2a
Acc ID: CHEBI:17315
Term: D-glucosamine
Definition: An amino sugar whose structure comprises D-glucose having an amino substituent at position 2.
Chemical ID: MESH:D005944
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDGlucosamine results in decreased expression of MEF2A mRNA

Glucosamine results in decreased expression of MEF2A protein

PMID:20165829
multiple interactionsEXP 6480464CTD4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]

4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]

ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]

ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]

tauroursodeoxycholic acid inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]

tauroursodeoxycholic acid inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]

PMID:20165829
decreases expressionISORGD:13221266480464CTDGlucosamine results in decreased expression of MEF2A mRNA

Glucosamine results in decreased expression of MEF2A protein

PMID:20165829
multiple interactionsISORGD:13221266480464CTD4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]

4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]

ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]

ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]

tauroursodeoxycholic acid inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]

tauroursodeoxycholic acid inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]

PMID:20165829
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.