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GENE - TERM ANNOTATION REPORT

RGD ID: 1359321
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gnb4
Name: G protein subunit beta 4
Acc ID: GO:0005834
Term: heterotrimeric G-protein complex
Definition: Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G protein-coupled receptors to an effector protein.
Definition Source(s): ISBN:0198547684
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gnb4part_ofISOGnb4 (Mus musculus)1624291RGDPR:Q9JMF3 PMID:10570481

PMID:10570481
Gnb4part_ofIEAUniProtKB:P29387 or ensembl:ENSMUSP000001211271600115EnsemblGO_REF:0000107

GO_REF:0000107
Gnb4part_ofIBAFB:FBgn0001105 or FB:FBgn0004623 or MGI:104581 or MGI:95781 or MGI:95785 or PANTHER:PTN000457487 or PomBase:SPBC32H8.07 or Gnb1 (Rattus norvegicus) or SGD:S000005738 or TAIR:locus:2139489 or UniProtKB:P11017 or UniProtKB:P62871 or UniProtKB:P62873 or dictyBase:DDB_G02771431600115GO_CentralGO_REF:0000033

GO_REF:0000033
Gnb4part_ofIEAPANTHER:PTHR19850:SF281600115TreeGrafterGO_REF:0000118

GO_REF:0000118
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