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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1359136
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ints12
Name: integrator complex subunit 12
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ints12increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of INTS12 mRNAPMID:33387578
Ints12affects expressionISOInts12 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of INTS12 mRNAPMID:21570461
Ints12decreases expressionISOINTS12 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of INTS12 mRNAPMID:17101203
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