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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1354455
Species: Homo sapiens
RGD Object: Gene
Symbol: SLC14A1
Name: solute carrier family 14 member 1 (Kidd blood group)
Acc ID: CHEBI:44423
Term: hydroxyurea
Definition: A member of the class of ureas that is urea in which one of the hydrogens is replaced by a hydroxy group. An antineoplastic used in the treatment of chronic myeloid leukaemia as well as for sickle-cell disease.
Chemical ID: MESH:D006918
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SLC14A1increases uptakeEXP 6480464CTDSLC14A1 protein results in increased uptake of HydroxyureaPMID:21256917
SLC14A1affects transportISOSlc14a1 (Mus musculus)6480464CTDSLC14A1 protein affects the transport of HydroxyureaPMID:17506977
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