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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1354258
Species: Homo sapiens
RGD Object: Gene
Symbol: CELSR1
Name: cadherin EGF LAG seven-pass G-type receptor 1
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CELSR1affects expressionEXP 6480464CTDValproic Acid affects the expression of CELSR1 mRNAPMID:25979313
CELSR1decreases expressionEXP 6480464CTDValproic Acid results in decreased expression of CELSR1 mRNAPMID:28001369
CELSR1increases expressionEXP 6480464CTDValproic Acid results in increased expression of CELSR1 mRNAPMID:23179753 PMID:27188386
CELSR1increases methylationEXP 6480464CTDValproic Acid results in increased methylation of CELSR1 genePMID:29154799
CELSR1affects expressionISOCelsr1 (Mus musculus)6480464CTDValproic Acid affects the expression of CELSR1 mRNAPMID:17963808
CELSR1increases expressionISOCelsr1 (Mus musculus)6480464CTDValproic Acid results in increased expression of CELSR1 mRNAPMID:21427059 PMID:27693483
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