Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1353986
Species: Homo sapiens
RGD Object: Gene
Symbol: ARG1
Name: arginase 1
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ARG1decreases expressionEXP 6480464CTDAcetaminophen results in decreased expression of ARG1 mRNAPMID:29067470 PMID:30008028
ARG1affects expressionISOArg1 (Rattus norvegicus)6480464CTDAcetaminophen affects the expression of ARG1 mRNAPMID:33387578
ARG1decreases expressionISOArg1 (Rattus norvegicus)6480464CTDAcetaminophen results in decreased expression of ARG1 mRNAPMID:18246545
ARG1increases expressionISOArg1 (Rattus norvegicus)6480464CTDAcetaminophen results in increased expression of ARG1 mRNA; Acetaminophen results in increased expression of ARG1 proteinPMID:16538041 PMID:16538043 PMID:8878780
ARG1increases expressionISOArg1 (Mus musculus)6480464CTDAcetaminophen results in increased expression of ARG1 mRNA; Acetaminophen results in increased expression of ARG1 proteinPMID:30375433 PMID:33887374
ARG1increases secretionISOArg1 (Mus musculus)6480464CTDAcetaminophen results in increased secretion of ARG1 proteinPMID:24038040
ARG1multiple interactionsISOArg1 (Mus musculus)6480464CTD[IL33 protein affects the susceptibility to Acetaminophen] which affects the expression of ARG1 mRNAPMID:33887374
Go Back to source page   Continue to Ontology report