GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | PLK1 | decreases response to substance | EXP | | 6480464 | CTD | PLK1 protein results in decreased susceptibility to Chromium | PMID:20089605 | PLK1 | multiple interactions | EXP | | 6480464 | CTD | 5-(5,6-dimethoxy-1H-benzimidazol-1-yl)-3-((2-(trifluoromethyl)benzyl)oxy)thiophene-2-carboxamide inhibits the reaction [Chromium results in decreased localization of PLK1 protein]; 5-(5,6-dimethoxy-1H-benzimidazol-1-yl)-3-((2-(trifluoromethyl)benzyl)oxy)thiophene-2-carboxamide inhibits the reaction [PLK1 protein results in decreased susceptibility to Chromium]; [5-(5,6-dimethoxy-1H-benzimidazol-1-yl)-3-((2-(trifluoromethyl)benzyl)oxy)thiophene-2-carboxamide co-treated with Chromium] results in increased activity of PLK1 protein; Chromium results in decreased expression of and results in decreased localization of PLK1 protein | PMID:20089605 | |
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