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GENE - TERM ANNOTATION REPORT

RGD ID: 1353799
Species: Homo sapiens
RGD Object: Gene
Symbol: NCBP2L
Name: nuclear cap binding protein subunit 2 like
Acc ID: GO:0005846
Term: nuclear cap binding complex
Definition: A conserved heterodimeric protein complex that binds to the 5' terminal cap structure m7G(5')ppp(5')N of nascent eukaryotic RNA polymerase II transcripts such as pre-mRNA and U snRNA. The consists of proteins known as CBP20 and CBP80, binds to cap structures in the nucleus, and is involved in pre-mRNA splicing, 3'-end formation, and RNA nuclear export.
Definition Source(s): PMID:16043498
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NCBP2Lpart_ofIBAPANTHER:PTN000428749 or Ncbp2 (Rattus norvegicus) or SGD:S000006099 or UniProtKB:P52298 or UniProtKB:Q585L4150520179GO_Central GO_REF:0000033
NCBP2Lpart_ofIEAInterPro:IPR027157150520179InterPro GO_REF:0000002
NCBP2Lpart_ofIEAPANTHER:PTHR18847:SF5150520179TreeGrafter GO_REF:0000118
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