GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | IL12B | decreases expression | ISO | Il12b (Mus musculus) | 6480464 | CTD | pirinixic acid results in decreased expression of IL12B protein | PMID:20131406 | IL12B | increases expression | ISO | Il12b (Rattus norvegicus) | 6480464 | CTD | pirinixic acid results in increased expression of IL12B mRNA | PMID:19162173 | IL12B | multiple interactions | ISO | Il12b (Mus musculus) | 6480464 | CTD | [Picryl Chloride co-treated with pirinixic acid] results in decreased expression of IL12B protein; pirinixic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]; PPARA protein affects the reaction [[Picryl Chloride co-treated with pirinixic acid] results in decreased expression of IL12B protein] | PMID:15968640 PMID:17371993 | | ||||||||||||||||||||||
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