GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | TERT | increases expression | EXP | | 6480464 | CTD | Raloxifene Hydrochloride results in increased expression of TERT mRNA | PMID:16798746 | TERT | increases phosphorylation | EXP | | 6480464 | CTD | Raloxifene Hydrochloride results in increased phosphorylation of TERT protein | PMID:16798746 | TERT | multiple interactions | EXP | | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Raloxifene Hydrochloride results in increased activity of TERT protein]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Raloxifene Hydrochloride promotes the reaction [RELA protein binds to TERT protein]]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Raloxifene Hydrochloride results in increased activity of TERT protein]; [Raloxifene Hydrochloride co-treated with PX-866] results in decreased expression of TERT mRNA; ESR1 protein promotes the reaction [Raloxifene Hydrochloride results in increased activity of TERT protein]; ESR2 protein promotes the reaction [Raloxifene Hydrochloride results in increased activity of TERT protein]; Raloxifene Hydrochloride promotes the reaction [RELA protein binds to TERT protein]; Raloxifene Hydrochloride results in increased expression of and results in increased activity of TERT protein; SN50 peptide inhibits the reaction [Raloxifene Hydrochloride results in increased activity of TERT protein] | PMID:16798746 PMID:27017931 | TERT | multiple interactions | ISO | Tert (Rattus norvegicus) | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Raloxifene Hydrochloride results in increased activity of TERT protein]; Raloxifene Hydrochloride promotes the reaction [TERT protein binds to RELA protein]; Raloxifene Hydrochloride results in increased phosphorylation of and results in increased activity of TERT protein | PMID:15590986 | | ||||||||||||||||||||||
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