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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1353330
Species: Homo sapiens
RGD Object: Gene
Symbol: PPP1R3F
Name: protein phosphatase 1 regulatory subunit 3F
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PPP1R3Faffects methylationEXP 6480464CTDBenzo(a)pyrene affects the methylation of PPP1R3F 3' UTR; Benzo(a)pyrene affects the methylation of PPP1R3F exon; Benzo(a)pyrene affects the methylation of PPP1R3F promoterPMID:27901495
PPP1R3Fincreases expressionISOPpp1r3f (Mus musculus)6480464CTDBenzo(a)pyrene results in increased expression of PPP1R3F mRNAPMID:22228805
PPP1R3Fmultiple interactionsISOPpp1r3f (Mus musculus)6480464CTDAHR protein affects the reaction [Benzo(a)pyrene affects the expression of PPP1R3F mRNA]PMID:22228805
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