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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1353141
Species: Homo sapiens
RGD Object: Gene
Symbol: LRRK2
Name: leucine rich repeat kinase 2
Acc ID: CHEBI:17846
Term: (S)-naringenin
Definition: The (S)-enantiomer of naringenin.
Chemical ID: MESH:C005273
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
LRRK2decreases expressionISOLrrk2 (Rattus norvegicus)6480464CTDnaringenin results in decreased expression of LRRK2 mRNAPMID:34655599
LRRK2multiple interactionsISOLrrk2 (Rattus norvegicus)6480464CTDnaringenin inhibits the reaction [Paraquat results in decreased expression of LRRK2 mRNA]PMID:34655599
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