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GENE - TERM ANNOTATION REPORT

RGD ID: 1352992
Species: Homo sapiens
RGD Object: Gene
Symbol: KCNJ2
Name: potassium inwardly rectifying channel subfamily J member 2
Acc ID: DOID:9005141
Term: Ventricular Tachycardia
Definition: An abnormally rapid ventricular rhythm usually in excess of 150 beats per minute. It is generated within the ventricle below the BUNDLE OF HIS, either as autonomic impulse formation or reentrant impulse conduction. Depending on the etiology, onset of ventricular tachycardia can be paroxysmal (sudden) or nonparoxysmal, its wide QRS complexes can be uniform or polymorphic, and the ventricular beating may be independent of the atrial beating (AV dissociation).
Definition Source(s): MESH:D017180
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
KCNJ2 EXP 11554173CTDCTD Direct Evidence: marker/mechanismPMID:17546530
KCNJ2 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Ventricular tachycardiaPMID:16217063 PMID:16818210 PMID:17341397 PMID:22581653 PMID:22589293 PMID:22806368 PMID:23631430 PMID:23644778 PMID:24861851 PMID:25741868 PMID:26304528 PMID:28336205 PMID:28492532
KCNJ2 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Ventricular tachycardiaPMID:15851159 PMID:15911703 PMID:22581653
KCNJ2 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Ventricular tachycardiaPMID:16818210 PMID:19843922 PMID:22581653
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