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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1352981
Species: Homo sapiens
RGD Object: Gene
Symbol: S100A9
Name: S100 calcium binding protein A9
Acc ID: CHEBI:27363
Term: zinc atom
Definition: A zinc group element atom that has formula Zn.
Chemical ID: MESH:D015032
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
S100A9affects bindingEXP 6480464CTDZinc binds to [S100A8 protein binds to S100A9 protein]PMID:17050004
S100A9multiple interactionsEXP 6480464CTD[Zinc co-treated with Calcium] binds to [S100A8 protein binds to S100A9 protein]PMID:17050004
S100A9increases expressionISOS100a9 (Rattus norvegicus)6480464CTDZinc deficiency results in increased expression of S100A9 mRNA; Zinc deficiency results in increased expression of S100A9 proteinPMID:19111725 PMID:22689922
S100A9increases expressionISOS100a9 (Mus musculus)6480464CTDZinc deficiency results in increased expression of S100A9 mRNAPMID:20857495
S100A9multiple interactionsISOS100a9 (Rattus norvegicus)6480464CTDZinc inhibits the reaction [Zinc deficiency results in increased expression of S100A9 mRNA]PMID:19111725
S100A9multiple interactionsISOS100a9 (Mus musculus)6480464CTDPTGS2 gene mutant form promotes the reaction [Zinc deficiency results in increased expression of S100A9 mRNA]; PTGS2 gene mutant form promotes the reaction [Zinc deficiency results in increased expression of S100A9 protein]; Zinc inhibits the reaction [PTGS2 gene mutant form promotes the reaction [Zinc deficiency results in increased expression of S100A9 mRNA]]; Zinc inhibits the reaction [PTGS2 gene mutant form promotes the reaction [Zinc deficiency results in increased expression of S100A9 protein]]PMID:20857495
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