GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | AKR1C3 | affects expression | EXP | | 6480464 | CTD | Valproic Acid affects the expression of AKR1C3 mRNA | PMID:25979313 | AKR1C3 | decreases methylation | EXP | | 6480464 | CTD | Valproic Acid results in decreased methylation of AKR1C3 gene | PMID:29154799 | AKR1C3 | increases expression | EXP | | 6480464 | CTD | Valproic Acid results in increased expression of AKR1C3 mRNA | PMID:23179753 PMID:24383497 PMID:24935251 PMID:25192806 PMID:26272509 PMID:26705709 PMID:28001369 | AKR1C3 | multiple interactions | EXP | | 6480464 | CTD | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C3 mRNA | PMID:27188386 | AKR1C3 | affects expression | ISO | Akr1c18 (Mus musculus) | 6480464 | CTD | Valproic Acid affects the expression of AKR1C18 mRNA | PMID:17292431 | |
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