GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | RELA | increases expression | ISO | Rela (Mus musculus) | 6480464 | CTD | Diethylnitrosamine results in increased expression of RELA protein | PMID:20583210 PMID:27151938 PMID:36442531 | RELA | increases expression | ISO | Rela (Rattus norvegicus) | 6480464 | CTD | Diethylnitrosamine results in increased expression of RELA mRNA; Diethylnitrosamine results in increased expression of RELA protein; Diethylnitrosamine results in increased expression of RELA protein modified form | PMID:19539802 PMID:21167192 PMID:21554863 PMID:24954034 | RELA | increases localization | ISO | Rela (Rattus norvegicus) | 6480464 | CTD | Diethylnitrosamine results in increased localization of RELA protein | PMID:19539802 | RELA | increases phosphorylation | ISO | Rela (Mus musculus) | 6480464 | CTD | Diethylnitrosamine results in increased phosphorylation of RELA protein | PMID:29859236 | RELA | multiple interactions | ISO | Rela (Mus musculus) | 6480464 | CTD | [Dietary Fats co-treated with Dietary Sugars co-treated with Diethylnitrosamine] results in increased phosphorylation of RELA protein; [Hexachlorobenzene co-treated with Diethylnitrosamine] results in increased expression of RELA protein; Cholecalciferol inhibits the reaction [[Hexachlorobenzene co-treated with Diethylnitrosamine] results in increased expression of RELA protein]; Cholic Acid promotes the reaction [Diethylnitrosamine results in increased expression of RELA protein]; CTNNB1 protein promotes the reaction [Diethylnitrosamine results in increased expression of RELA protein]; Diethylnitrosamine affects the phosphorylation of and affects the activity of RELA protein; Diethylnitrosamine promotes the reaction [[Dietary Fats co-treated with Dietary Sugars] results in increased expression of RELA mRNA]; Diethylnitrosamine promotes the reaction [[Dietary Fats co-treated with Dietary Sugars] results in increased expression of RELA protein]; Fosinopril inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of RELA protein]; Losartan inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of RELA protein]; Perindopril inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of RELA protein]; scoparone affects the reaction [[Dietary Fats co-treated with Dietary Sugars co-treated with Diethylnitrosamine] results in increased phosphorylation of RELA protein]; scoparone inhibits the reaction [Diethylnitrosamine promotes the reaction [[Dietary Fats co-treated with Dietary Sugars] results in increased expression of RELA mRNA]]; scoparone inhibits the reaction [Diethylnitrosamine promotes the reaction [[Dietary Fats co-treated with Dietary Sugars] results in increased expression of RELA protein]]; Sorafenib inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of RELA protein]; Vitamin D inhibits the reaction [Diethylnitrosamine results in increased expression of RELA protein] | PMID:20583210 PMID:21159647 PMID:27151938 PMID:28634113 PMID:29859236 PMID:36442531 PMID:37436232 | RELA | multiple interactions | ISO | Rela (Rattus norvegicus) | 6480464 | CTD | 5,7-dimethoxyflavone inhibits the reaction [Diethylnitrosamine results in increased expression of RELA mRNA]; 5,7-dimethoxyflavone inhibits the reaction [Diethylnitrosamine results in increased expression of RELA protein modified form]; [Dietary Fats co-treated with Diethylnitrosamine] results in increased expression of RELA protein; [Diethylnitrosamine co-treated with ferric nitrilotriacetate] results in increased localization of RELA protein; [Diethylnitrosamine co-treated with N-nitrosomorpholine] results in increased expression of RELA protein; Chloroquine inhibits the reaction [[Diethylnitrosamine co-treated with N-nitrosomorpholine] results in increased expression of RELA protein]; chrysin inhibits the reaction [[Diethylnitrosamine co-treated with ferric nitrilotriacetate] results in increased localization of RELA protein]; chrysin inhibits the reaction [Diethylnitrosamine results in increased expression of RELA mRNA]; chrysin inhibits the reaction [Diethylnitrosamine results in increased expression of RELA protein]; Diethylnitrosamine results in increased activity of [NFKB1 protein binds to RELA protein]; Diethylnitrosamine results in increased activity of and results in increased localization of RELA protein; morin inhibits the reaction [Diethylnitrosamine results in increased expression of RELA mRNA]; morin inhibits the reaction [Diethylnitrosamine results in increased expression of RELA protein]; morin inhibits the reaction [Diethylnitrosamine results in increased localization of RELA protein]; O-(Chloroacetylcarbamoyl)fumagillol inhibits the reaction [Diethylnitrosamine results in increased activity of [NFKB1 protein binds to RELA protein]]; Resveratrol inhibits the reaction [Diethylnitrosamine results in increased activity of and results in increased localization of RELA protein]; Roxithromycin inhibits the reaction [Diethylnitrosamine results in increased activity of [NFKB1 protein binds to RELA protein]] | PMID:16061884 PMID:19004024 PMID:19539802 PMID:20405173 PMID:21167192 PMID:21554863 PMID:23194824 PMID:24990399 | | ||||||||||||||||||||||
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